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asa glp-1 agonist guidelines GLP1 agonists: current and future landscape of clinical trials for patients with metabolic dysfunction How should GLP-1 receptor agonists
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FEBS Lett 1996

About this article Cite this article Giugliano, D., Scappaticcio, L., Longo, M

10.3892/etm.2019.7347 107 WangL.LiP.TangZ.YanX.FengB

Conclusions: GLP-1 RAs represent a paradigmatic shift toward multi-system therapeutic intervention, with expanding evidence supporting their role as comprehensive metabolic modulators

27 Interestingly, a meta-analysis discussed the efficacy of different types of drugs, including anti-fibrotic, anti-metabolic, and anti-apoptotic agents, on MASH and fibrosis

Furthermore, GLP-1RAs can increase diuretic and natriuretic actions through changes in renal hemodynamics and inhibition of the sodium-hydrogen exchanger 3 in the renal proximal tubule [56]
