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PG004 Semaglutide biosimilar Pipeline Obesity and Diabetes Semaglutide Semaglutide Biosimilar A new game changer in the diabetes and obesity treatment market Features Next generation obesity and diabetes treatment based on GLP-1 analogue that lasts for one week Maintaining blood sugar through regulation of insulin and glucagon secretion Weight loss by suppressing appetite through nervous system Originator Mechanism Semaglutides core mechanism of action Its an analog of GLP-1(glucagon-like peptide-1) and activated the gastrointestinal hormone incretin to control blood sugar levels and reduce weight Obesity Semaglutide delays the rate at which food is expelled from the stomach and acts on the appetite center to suppress appetite and increase satiety, thereby reducing the amount of food consumed and resulting in weight loss Diabetes Semaglutide regulates blood sugar by stimulating pancreatic beta cells to increase insulin secretion and inhibiting glucagon secretion Alzheimer's Phase 3 clinical trials for Alzheimer's disease are currently underway Equivalence analysis results LC and MS analysis confirmed more than 99% similarity to the originator As a result of cAMP analysis using a GLP-1 recptor expressing cell line, it was confirmed to be more than 99% similar to the originator Semaglutide biosimilar research and development results As a result of the development of a semaglutide biosimilar, PEPGENE has completed the development of a biosimilar that is more than 99% similar to the original semaglutide

Cardiovascular exercise supports both weight loss and thyroid health

Regulatory environment & payer interest: Because obesity and type 2 diabetes are recognized large unmet markets, there is likely strong interest from regulators and payers in therapies that are effective, more convenient, possibly less expensive

Lilly CEO David Ricks told CNBC late last month that establishing Foundayo as a brand would "take some time." Foundayo uses a different active ingredient than Lilly's blockbuster injectables Mounjaro and Zepbound, while Novo's Wegovy pill is essentially an extension of the company's injectable equivalents

He added that some studies have suggested weight-loss drugs could increase pharmacy spending by more than 20 percent over the next few years

More frequent dental cleanings and examinations may be beneficial during the initial months of GLP-1 treatment when side effects are typically most pronounced