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Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (81930019, 82341076) to Jin-Kui Yang

19 Chronic disabling headaches occur in the majority and have adverse impact on quality of life

A normal BMI with metabolic issues would not qualify under the weight management pathway

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The result: poor sleep night after night

The enzymes is called DPP-4 (dipeptidyl peptidase-4) and the new medications are called DPP-4 inhibitors or gliptins