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GLP-1 receptor agonists and dual GLP-1/GIP agonists are highly effective for weight loss and cardiometabolic improvement in menopausal women, though most data still come from non-menopause-specific obesity trials (STEP, SELECT, SURMOUNT)

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While fat is targeted for the most part initially, it is not unusual for some of the needed energy to come from your muscle as well

GLP-1R agonists, including semaglutide and liraglutide, have demonstrated significant cardioprotective effects, such as improving vascular endothelial function, reducing inflammation, and preventing atherosclerosis

Its glucagon receptor activity also makes it a subject of interest in hepatic fat research independent of body weight effects
