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Beyond these, in the pre-clinical space, over 25 candidates have been disclosed, but our analysis of patents, company disclosures, and early-stage publications identifies nearly 70 additional undeclared pre-clinical programs

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- - - A new Oxford meta-analysis (P04.009, EASO 2025) confirms what many clinicians have observed: stopping GLP-1 receptor agonists often leads to rapid and near-complete weight regain within 12 years