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Long-term hyperglycemia promotes renin and angiotensin II synthesis in mesangial cells, leading to elevated glomerular capillary pressure and permeability, which are key components in the development of proteinuria

[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Marino-Fernndez A.G., Garca-Gutirrez I., Alonso Juaristi S., Lpez Gutirrez J., Tawfiq Piedad M., Guerrero Sotelo .L., Albarracn Contreras .J., Ortiz Aljaro P., Rodrguez Fernndez F
In comparison with exenatide twice daily, lixisenatide also showed decreased rates of nausea
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