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[13] The participants were randomly assigned to receive semaglutide or placebo
Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing

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doi: 10.1200/JCO.2005.05.1847

Reduced blood flow to genital tissues decreases natural lubrication and overall sensation, making penetrative sex uncomfortable and reducing the arousal response that normally precedes and accompanies it
