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Novo Nordisk is using this strategy to defend and extend its obesity leadership beyond semaglutide alone
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Additionally, obesity itself increases abdominal pressure and weakens the lower esophageal sphincter (LES), the muscle that prevents acid backflowso initial weeks of rapid weight loss may temporarily worsen reflux before digestive physiology normalizes
M., Woodward, M., Zheng, W., Zhou, M., Bansal, N.,
Abdelmalek M, Choi J, Kim Y, et al
