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Preclinical studies using the combination of leptin and other hormones have provided insights into potential new approaches for obesity treatment (16)

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[,,] In Figure 6 DPP-4stands for Dipeptidyl Peptidase-4

Tirzepatide acts on both GIP and GLP-1 receptors, while semaglutide acts only on GLP-1 receptors, leading to somewhat different effects

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