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Targeting the Notch and TGF- signaling pathways to prevent retinal fibrosis in vitro and in vivo

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Phase 2 clinical trials involved 338 adults with obesity (BMI 30 or more) and overweight (BMI of 2729.99) with one or more weight-related conditions such as high blood pressure, high cholesterol levels, heart disease, and type 2 diabetes

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Given that semaglutide may protect vascular structure and improve endothelial permeability, treatment may provide additional benefits to this subpopulation of participants in evoke+

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