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A novel triple receptor agonist conferred weight loss of up to 28.7% at 68 weeks and reductions in pain for adults with overweight or obesity and knee osteoarthritis, according to topline results from the TRIUMPH-4 trial

New preclinical study provides novel insights into how GIP and GLP-1 work together in the brain to drive weight loss

Compared to WT controls, lymphatics from ApoE KO mice displayed significant contractile dysfunction, which was restored with semaglutide

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Key implications: Simplified administration may improve patient uptake Broader accessibility across diverse healthcare settings Reinforces the shift toward chronic disease models in obesity care As we move forward, the focus will not only be on efficacy but also on real-world implementation, cost considerations, and long-term outcomes

Well, for starters, its not about willpower