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Description
Botox, originally approved by the FDA in 2002 for cosmetic use, has a history that dates back to the late 1970s when it was first used medically to treat muscle spasms

GLP-1/GIP medications combine GLP-1 with GIP, a second hormone that enhances insulin sensitivity and fat metabolism

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10-13 In subsequent trials where higher doses of the GLP-1/GIP agonists were used in non-diabetic obese subjects, weight loss of 15% to 21% of body weight was seen

Some estimates suggest that perimenopausal women make up the majority of users

The medication may affect how pleasurable certain foods feel, potentially reducing the drive to consume highly palatable, energy-dense foods including those high in sugar
