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Comparison of clinical outcomes and adverse events associated with glucose-lowering drugs in patients with type 2 diabetes: a meta-analysis

After 5 days of treatment, rats treated with MK-801, semaglutide or GLP-1MK-801 had significantly decreased body weight compared with the vehicle-treated rats

9,293 Views 85 Download 1 Crossref ABSTRACT Obesity is a disease requiring treatment

Excellent fiber sources include: Oats and oat bran Barley and whole grains Flaxseeds and chia seeds Avocados Brussels sprouts, broccoli, and leafy greens Berries (raspberries, blackberries) Apples and pears with skin Resistant starch sources (cooled potatoes, green bananas) Healthy fats may also contribute to GLP-1 secretion, though the response may be somewhat delayed compared to other nutrients

While the inflammation-reducing and fibrosis-attenuating effects of glucagon agonism are less well-characterized, the reductions in hepatic inflammation parameters and fibrosis observed in preclinical models likely reflect secondary effects consequent to improved steatosis, rather than direct anti-inflammatory actions [21]
