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A heavier person distributes the same dose across more tissue, resulting in lower peak levels
Rapid improvements in blood glucose levels can temporarily worsen diabetic retinopathy in some individuals
This has an influence on how insulin is released, how fast the stomach empties, and how the body controls hunger
Until more is known, the safest approach is to avoid it during pregnancy
Some patients or clinicians halt titration at intermediate doses when side effects emerge, rather than allowing time for gastrointestinal adaptation
