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Contrave (naltrexone/bupropion) Approved - An oral medication combining an opioid antagonist and an antidepressant

Hair grows approximately 1-1.25 cm per month

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Reference lists of key studies and review articles were manually screened to ensure completeness, and citation tracking was performed to identify additional relevant publications

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Preclinical studies suggest that dual GLP-1/GIP agonism enhances endothelial function, reduces vascular inflammation, and promotes plaque stability more effectively than GLP-1 alone, potentially via amplified cAMP signalling and GIP-mediated anti-lipolytic effects [52]