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A 2026 review in Drugs lays out the clinical tension clearly: maternal obesity + excess gestational weight gain drive major short- and long-term risks for both mother and baby, while lifestyle-only strategies often deliver modest resultscreating a real unmet need

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Proper storage directly impacts medication efficacy and safety

Results The first cohort included 36082 GLP-1 receptor agonist users (median follow-up 1.3 years) and 234028 DPP-4 inhibitor users (median follow-up 1.7 years)

This allows compound 2 to execute positive allosteric modulation through enhancement of both agonist binding and G protein coupling