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They are both administered via subcutaneous injection and have similar side effects

Br J Diabetes 2021

Its function in macrophages was first identified in 2006, revealing that Trem2 plays a crucial role in restraining macrophage activation [34]

[DOI] [PMC free article] [PubMed] [Google Scholar] 197.Patel K.A., Kettunen J., Laakso M., Stancakova A., Laver T.W., Colclough K., et al

Patients who complete clinical studies may be more motivated than average, and results should not be assumed to be typical

Weeks 1 to 4: the GI phase During the initial weeks, particularly during the 0.25 mg starting dose and the first escalation to 0.5 mg, GI side effects dominate