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Description
Knockout of insulin receptor in mice results in slight growth retardation at birth, but no metabolic abnormalities are present

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compared to $444 in the Netherlands and $319 in Japan

Glucose tolerance test In the 13th week, mice were randomized and subjected to pharmacological dosing (six mice/group)
This has increased the possibility of hypothalamic leptin resistance in IIH

After 4 weeks of 0.25 mg, increase dose to 0.5 mg once weekly