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PMID 22105373

This data directly informs the necessity of a washout period

This hormone tells your brain you feel full, slows digestion, and reduces appetite
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As of March 29, 2026 , retatrutide remains investigational , not FDA approved

In people with type 1 diabetes, the pancreas does not produce enough insulin, but with Type 2 diabetes, the pancreas produces enough insulin, but the body is not able to process it properly
