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We discuss the use of glucagon-like peptide-1 (GLP-1) analogues as monotherapy and unimolecular dual or triple agonists that exploit the GLP-1 receptor and/or the gastric inhibitory peptide (GIP) receptor and/or the glucagon receptor

The cost, the shortages, and even the side effects have led to older people who start Ozempic, Wegovy, and similar drugs to stop them after a few months.

The study highlights that after stopping GLP-1 medications, many patients resume treatment or try alternatives, influencing weight management strategies.

Initially approved for diabetes treatment under the name Ozempic, it became a recognized treatment for obesity as Wegovy

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De Giorgi and colleagues present a comprehensive analysis of pre-clinical and clinical studies examining the role of glucagon-like peptide-1 receptor agonists in mental disorders.