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The expected weight loss due to loss of up to 400 kcal energy into the urine may be as much as 11 kg [40], but a compensatory increase of food intake probably accounts for the partial off-set of weight loss

GLP-1s (glucagon-like peptide-1 receptor agonists) help regulate blood sugar, slow digestion, and suppress appetite

Has side effects such as chest pain, palpitations, numbness and tingling of hands

It is a peptide in the strict biochemical sense: a chain of amino acids designed to mimic and amplify the action of GLP-1, a hormone the gut naturally releases after eating

Mindfulness and acceptance-based interventions, such as mindfulness-based cognitive therapy, mindfulness-based stress reduction, and acceptance and commitment therapy, are therapeutic approaches to enhance psychological flexibility, awareness, and non-judgmental acceptance of present-moment experiences, including bodily sensations, thoughts, and feelings [220]

Across five illustrative GLP-1 scenarios, a ~10g supplement lifts total fiber to between 18 and 27g a day