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Tirzepatide (Mounjaro/Zepbound) Discontinuation Patterns The SURMOUNT trials havent published official discontinuation data yet because patients are still being tracked

But their broad adoption raises questions about access, cost, off-label use, and long-term safety

Wang, X., Cheng, R., Cheng, L

Starting at a low dose and increasing gradually over weeks or months means that the full therapeutic dose is reached after the gastrointestinal system has had time to adjust to lower amounts of the medication