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Henry Meds reviewed: program model, medication options, eligibility, pricing, and editorial context
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patients had CKD stages 1 to 5 diagnosed by Kidney Disease: Improving Global Outcomes guidelines plus at least 3 months of one of the following: moderate to severe albuminuria regardless of estimated glomerular filtration rate (eGFR), eGFR less than 90 mL/min/1.73 m2 with structural abnormalities of the kidney or urinary sediment abnormalities, or eGFR less than 60 mL/min/1.73 m2
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The mouse models included lean mice (C57BL/6J and NSY.B6- a / a ), obese diabetic mice (NSY.B6- Ay / a ), proglucagon-deficient mice ( Gcg -/-), glucose-dependent insulinotropic polypeptide (GIP) receptor-deficient mice ( Gipr -/-), and ATP-sensitive potassium channel (KATP channel)-deficient mice ( Kcnj11 -/-)