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Future innovations will build on this foundation, offering even better tools for managing obesity and metabolic disease

Serious side effects including pancreatitis, gallbladder issues, and acute kidney injury are rare but require immediate medical attention if suspected

[9] [19] At the conclusion of phase II clinical trials, Saniona announced that tesofensine was well tolerated with low incidence of adverse events, low increase in heart rate and no significant effect on blood pressure

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doi: 10.1016/S0140-6736(21)02188-7 Dahl D, Onishi Y, Norwood P, et al

GIP Receptor Benefits The addition of GIP receptor agonism provides unique benefits: GIP enhances insulin secretion with a different kinetic profile than GLP-1, potentially improves insulin sensitivity in peripheral tissues, may enhance energy expenditure through thermogenic effects in adipose tissue, and appears to reduce food intake through complementary central mechanisms