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Description
Hypoglycemia especially in patients with type 2 diabetes who are also taking insulin or sulfonylureas
Confirmatory testing using GC-MS or LC-MS/MS methodology is standard practice for employment drug testing and is explicitly required in DOT and federal workplace programs before any adverse action can be taken
Tirzepatide was initially developed as a medication to treat type 2 diabetes and has more recently been approved for weight management, with users experiencing other metabolic benefits
Slower titration schedules may reduce early GI side effects
Some providers specifically recommend microdosing for this population to allow metabolic adjustment without exacerbating hormonal symptoms
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