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By 2020, an estimated 2.2 billion adults worldwide were suffering from overweight and obesity, and it is predicted that this number will increase to 3.3 billion by 2035 [1]

The net effect of the mismatch between increased ATP demand and decreased ATP generation is increased renal oxygen consumption, ultimately rendering the kidney susceptible to renal hypoxia [15]

In the 30-49 age group, 3% had used GLP-1s to treat chronic conditions, 6% for weight loss, and 2% for both

Retatrutide may be worth waiting for if: You have not responded adequately to existing GLP-1 medications Your obesity is severe enough to benefit from the additional weight loss potential You have metabolic dysfunction-associated steatotic liver disease (MASLD/NAFLD) You are comfortable with a medication that has less real-world safety data You can wait for FDA approval without significant health deterioration Your cardiovascular status has been evaluated and heart rate increases are not contraindicated Retatrutide represents the next frontier

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Watch Now Agenda *Agenda subject to change 6:30 PM Guest Arrival and Cocktail Reception 7:00 PM Welcome Participants Tyler Watson Executive Vice President of Marketing, The Atlantic Susan Sweeney Executive Vice President of Obesity and Related Conditions, Amgen 7:05 PM The Defining Scale Shift in Obesity Therapeutics Summary The first wave of obesity medications proved that biology works and sparked extraordinary demand