arcadia biosciences glp-1 receptor agonist weight management diabetes treatments JCI GLP-1 Receptor Agonists: From Diabetes

The approval of Reblozyl in the first-line treatment of anemia for patients with lower-risk MDS represents a crucial step in making transfusion independence possible for more patients. Results from the COMMANDS study were featured in June as part of the press program at the American Society of Clinical Oncology (ASCO) Annual Meeting and plenary session at the European Hematology Association (EHA) Congress, with simultaneous publication in The Lancet

There are large gaps in research with GLP-1RA, noting future large-scale clinical trials are needed for dietary supplement interventions

For those with IBS-D (diarrhoea-predominant IBS), there can be some improvements in bowel urgency and/or frequency

Risk of thyroid cancer associated with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes: A population-based cohort study

doi: 10.1016/j.neuropharm.2019.107668 105 SiddiquiNAliJParvezSZameerSNajmiAKAkhtarM

GLP-1 is constantly secreted from the intestine at low basal levels in the fasted and interprandial state, and circulating GLP-1 levels increase 2- to 3-fold after nutrient ingestion