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What strategies do you recommend to reduce the risk of rebound weight gain if I stop the drug

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Individuals with estimated glomerular filtration rate below 30 mL per min should use tirzepatide with caution, starting at 2.5 mg and escalating more slowly while monitoring renal function closely

Eating smaller, more frequent meals and avoiding large, fatty meals can help manage upset stomach

By extending earlier preclinical work on GLP-1 receptor agonists and alcohol intake to a task that directly assesses the subjective effects of alcohol, these findings provide important context for interpreting clinical observations of reduced drinking behavior among individuals receiving GLP-1 receptor agonist-based therapies

Together, they add up to a profound metabolic effect