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We keep learning more about the array of beneficial impacts that GLP-1 drugs have on the brain, a new 1st rate review @Cell_Metabolism, including: the neuro-glial-vascular unit, including integrity of the blood brain barrier (Figure) protection of myelin sheath reducing

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The STEP (Semaglutide Treatment Effect in People with Obesity) clinical trial programme demonstrated that adults using semaglutide 2.4 mg weekly alongside lifestyle intervention lost an average of approximately 15% of their body weight over 68 weeks, compared to around 2.4% with placebo. NICE approved Wegovy for use in specialist weight management services in the UK in 2023 (TA875), recognising its clinical effectiveness. Ongoing research continues to explore its cardiovascular benefits, with the SELECT trial showing a significant reduction in major cardiovascular events in people with obesity

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Yes, you can prescribe GLP-1 receptor agonists to diabetic patients who have had a cholecystectomy (no gallbladder)