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Effects of GLP-1-(736)NH2, GLP-1-(737), and GLP-1- (936)NH2 on Intravenous Glucose Tolerance and Glucose-Induced Insulin Secretion in Healthy Humans

2 With the use of GLP-1 receptor agonists becoming increasingly more common, anesthesia professionals need to be aware of these medications and the potential risks they pose to patients receiving anesthesia

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The AGA specifically suggests continuation of GLP1-RA use until the day or a week prior to the procedure for daily or weekly GLP1-RAs, respectively [195]

Pre-clinical experiments in DIO mice using this dual-agonist evidence greater weight lowering effects, food intake reductions, enhancements in energy expenditure, improvements in glycemic control, and reductions in hepatic steatosis, plasma cholesterol and triglycerides, all relative to the vehicle and a matched non-lactam bridge-containing (GLP-1R preferring) control peptide [43]
