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GLP-1RAs reduce events linked to atherogenic cardiovascular disease (especially ischemic stroke) and also renal outcomes (FLOW trial with semaglutide), with a limited effect on heart failure
Semaglutide (Wegovy 2.4 mg) The STEP trials, which evaluated semaglutide for weight loss, found that patients taking 2.4 mg of semaglutide weeklyachieved an average weight loss of 14.9% of their body weight over 68 weeks
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