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J Clin Investig 116(2):299302 Schroeder EB (2022) Management of type 2 diabetes: selecting amongst available Pharmacological agents

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It describes the hollowed, sagging, or slack appearance that can accompany rapid weight loss, particularly in the face and neck but also in the arms, abdomen, and chest

Studies show 2540% of weight lost on GLP-1 medications can be lean muscle without a protective plan
