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doi: 10.1111/j.1464-5491.2008.02484.x

GLP-1 receptor agonists are primarily FDA-approved for managing Type 2 diabetes and obesity

40 Nevertheless, accumulating evidence indicates that CR is detrimental to skeletal metabolism, as evidenced by reductions in BMD and bone mineral content (BMC), diminished bone formation indices (e.g., bone formation rate, osteoblast number), and a concomitant increase in bone resorption

[DOI] [PubMed] [Google Scholar] 9.Uhlen M., Fagerberg L., Hallstrom B.M., Lindskog C., Oksvold P., Mardinoglu A., Sivertsson A., Kampf C., Sjostedt E., Asplund A., et al

While the science on allulose and blood glucose regulation is promising, more large-scale human studies are needed

Smitha et al., 2014)