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Given the substantial disease burden and adverse health outcomes associated with this comorbidity, interventions aimed at reducing this risk for depression in the Type 2 diabetes population are crucial, particularly among older adults who are disproportionately affected by both conditions. Guo noted that previous research suggested that GLP-1RAs a drug also used to treat obesity and kidney disease may alleviate depression symptoms due to its ability to cross the blood-brain barrier

Makita, N., Manaka, K., Sato, J

Large amounts without sufficient fluid will almost certainly make constipation worse

Retatrutide phase 2 obesity trial investigators

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