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Semaglutide was associated with gastrointestinal adverse events (nausea, vomiting, diarrhea, constipation) which were of mild to moderate severity, short duration, and resolved without treatment discontinuation ( Notably, a recent systematic review showed that compared to other semaglutide doses and GLP-1 RAs, 2.4 mg semaglutide had the greatest effect on weight reduction, controlling glucose level, and reducing BP

In Eli Lillys TRIUMPH-1 Phase 3 trial (n=2,339), the compound produced a mean weight loss of 28.3% at 80 weeks in research models without type 2 diabetes

Its associated with long-term complications including hypertension, stroke, heart failure, and impaired quality of life

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Which GLP-1 medication may feel easier to tolerate during menopause

Sip water or a sugar-free drink while you snack