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Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats
7, 8 Normal human pancreas as well as the chronically inflamed pancreas express GLP1R, as expected, primarily in the therapeutic targets of GLP1 analogs, namely the insulin-producing cells

Two ideas explain most day to day appetite patterns: Satiety / reduced cravings, and the pace of digestion

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