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While tracking weight can motivate, the main goal is to understand how symptoms such as nausea, fatigue, and appetite suppression change throughout the week

More serious side effects are rare but should be discussed with a healthcare provider

(2025), in Diabetes, Obesity and Metabolism, reported a weighted mean difference of 1.02 kg in lean body mass across 19 RCTs

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as highly effective anti-obesity therapies, producing weight loss of approximately 520% across clinical trials

J Pharmacol Exp Ther, 356:223-231

Semaglutide is the most potent, achieving HbA 1c reductions up to 20 mmol/mol (Pratley et al, 2018), followed by dulaglutide, liraglutide, exenatide once weekly, and lixisenatide and exenatide twice daily (Nauck et al, 2021)