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We assessed the prespecified secondary outcome metabolic syndrome severity z-score (MetS-Z), abdominal obesity (estimated as android fat via dual-energy X-ray absorptiometry), and inflammation marker high-sensitivity C-reactive protein (hsCRP)

extending into the early 2030s, Novo Nordisk's core semaglutide patent has lapsed in Canada

Although these findings are preliminary, some mechanistic models posit that GLP-1s could attenuate DMNactivity associated with food-related rumination, potentially altering the cognitive context in which eating decisions occur

by Julia Lloyd, MPH, RD, LDN, CDCES Spring 2026 GLP-1 medications are changing how people manage weight, blood sugar and metabolic health

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It raises the risk of type 2 diabetes, heart disease, sleep problems, and depression conditions that already shadow many people with ADHD