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For clients managing type 2 diabetes, improvements in blood sugar levels can be seen within the first week or two

56 ReinerD

Given the increasing emphasis on the use of GLP-1 RAs in clinical practice, it is important that all members of the healthcare team, including pharmacy professionals, understand current recommendations and patient-specific considerations for use

The physiological action of the GLP-1/GIP axis hence rendered these gut hormones as attractive medicinal targets to treat T2D and, subsequently, obesity

PaulyRPDemuthHURoscheFSchmidtJWhiteHALynnFet al

The double mutation of N302 ECL2 -M303 ECL2 to Val-Lys caused a small affinity reduction with a 10-fold decrease in potency (Moon et al., 2012)
