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Overall, approximately 14-15% of patients experienced a clinically significant complication, defined as events requiring intervention, prolonged hospital stay, or intensive care admission

Arenson, D

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Likewise, exome sequencing of 40 unrelated individuals diagnosed with PA and hypertension by the age of 10 years identified five cases (12.5%) carrying the same CACNA1H (M1549V) mutation

Novo acquired exclusive rights to develop, manufacture, and commercialize UBT-251 outside of mainland China, Hong Kong, Macau, and Taiwan

These pro-inflammatory cytokines promote hepatic environment dysfunction, leading to mitochondrial dysfunction, oxidative stress, and endoplasmic reticulum (ER) stress, ultimately impairing insulin receptor substrate (IRS) signaling (140, 223)