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DeVries J

Semaglutide undergoes hepatic metabolism, but dehydration from GLP-1induced nausea or vomiting can indirectly stress kidney function and reduce methotrexate clearance

Under normal circumstances, your stomach empties its contents into the small intestine within two to four hours after eating

These medications work by steady receptor activation, not on-demand use

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doi: 10.1111/dom.14843 68 WilsonJMLinYLuoMJConsidineGCoxALBowsmanLMet al
