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GLP-1 medications also provide additional cardiovascular and metabolic benefits, including reduced blood pressure, improved cholesterol profiles, and enhanced insulin sensitivity

Less Recognized Adverse Effects A common finding amongst all GLP-1 trials was that of increased heart rate attributed to a direct effect on the pacemaker cells within the sinus node of the heart [185]

J Hypertens Suppl 1990;8:S3S8

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Hepatic and Metabolic Benefits A MAFLD/MASLD (metabolic dysfunction-associated steatotic liver disease) sub-study of the Phase 2 obesity trial reported that over 85% of participants on the highest retatrutide doses achieved more than 30% reduction in liver fat content measured by MRI, with many reaching complete resolution of steatosis

And yet retatrutide is for sale all over the internet, a phenomenon with no modern precedent