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Therefore, screening for lead compounds able to activate this essential enzyme might protect neuronal cells from damage and slow the disease progression

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We used two paradigms for ALA delivery: an intervention paradigm in which DBA/2J mice at 6 months of age received ALA in order to intervene in glaucoma development, and a prevention paradigm in which DBA/2J mice were raised on a diet supplemented with ALA, with the goal of preventing glaucoma development

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