glp 1 drugs vs phentermine Ozempic GLP-1 anti-obesity medicines remain too

However, tolerability, discontinuation rates, and comparative efficacy will be key watchpoints

Back Mojsov, S, Weir, GC, Habener, JF (Feb 1987) 'Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas', Journal of Clinical Investigation , 79, 616-19

GLP-1 receptor agonists and colorectal cancer risk in drug-naive patients with type 2 diabetes, with and without overweight/obesity

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The gastrointestinal adverse effect profile represents the most significant concern

While long-term clinical studies are ongoing, we can be carefully optimistic that improved GLP-1-based pharmacology can one day be safely applied to further lower body weight relative to currently available GLP-1R agonists