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A synthetic version was created in the years after, but it took until 2005 for this GLP-1 agonist to become an FDA-approved treatment for type 2 diabetes

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Oral forms, while innovative, have less historical data to guide their use

If you have pre-existing medical conditions such as diabetes, kidney disease, or cardiovascular disease, or if you are taking other medications (such as diuretics, statins, or blood pressure medications) that may increase cramping risk, inform your healthcare provider

During the first few months, these effects produce rapid weight loss

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