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The authors discuss the preclinical literature and emerging clinical evidence that support the rationale for investigating the use of glucagon-like peptide-1 receptor agonists to prevent and treat several neurodegenerative diseases of aging, with a focus on Alzheimers disease.

In the trial that got Zepbound approved, the average person on the highest 15 mg dose lost 20.9% of their body weight over 72 weeks

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The injectable drug, initially only used as diabetes medication, is the first drug since Saxenda (2014) approved to treat chronic weight management in the 70% of American adults who are obese or overweight.

Known widely in advanced metabolic literature and life-science forums as a GLP-3 peptide, this compound represents the latest breakthrough in multi-receptor