indications for glp-1 agonists What to know about the new era of drugs The expanding role of GLP-1
Description
A positive connectivity score (close to +1) indicates the compound has a gene expression profile similar to that of a specific drug

therefore, there has been a sense of caution about such use

10.1021/jm9909645 70 KoltermanO

The GI effects of GLP-1 drugs are actually part of their mechanism of action, not just unpleasant side effects

Front Med (Lausanne)
GLP-1 RAs, which perform hormonal appetite control
