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This difference was particularly striking within the distal mitotic germ cells, where GFP was about 25-fold higher in puf-8(/) mutants than in wild-type worms [ puf-8(+/+) ]
Around 50% of people discontinue GLP-1 RAs within the first year, yet these drugs offer significant benefits in both type 2 diabetes and obesity

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These effects include nausea, vomiting, diarrhea, abdominal pain, constipation, and gastroesophageal reflux disease (GERD) symptoms such as heartburn
