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The STAMPEDE (Surgical Therapy and Medications Potentially Eradicate Diabetes Efficiently) trial showed that metabolic surgery, when compared with intensive medical therapy (lifestyle counseling, weight management, self-monitoring of glucose, drug therapy), significantly improved outcomes for weight loss, DM remission, glycemic control, need for DM medications, lipid and BP medications, and QoL 777 Five-year outcomes from a 2020 RCT reported that Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding achieved remission of T2D in 30% and 19% of persons, respectively, compared with 0% of controls undergoing intensive lifestyle weight intervention

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Behavioral Counseling: Support to address emotional and psychological aspects of eating, helping adolescents build a positive relationship with food and body image

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In a study conducted in individuals with metabolic syndrome without diabetes or cerebrovascular event, liver enzymes and ultrasound improved during the study with the use of statins 37