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Retatrutide hit 28.3% weight loss in the May 2026 trial

For many women, both perimenopause and menopause feels like the moment their body suddenly starts playing by different rules

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These effects are primarily seen in obese patients with preserved renal and cardiac function and may not generalize to all HFpEF phenotypes

Major adverse cardiovascular events (composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke), changes from baseline in glycated hemoglobin A1c (HbA1c) and body weight, and adverse events were analyzed